张冬冬
个人简介
中国海洋大学 生物科学学士,中国海洋大学 水生生物学硕士,美国奥本大学(Auburn University)水产渔业科学博士。2019年10月入职永利集团,副教授,海南省D类高层次人才。主持国家自然科学基金、海南省自然科学基金等多项科研项目,在 Fish and Shellfish Immunology和Aquaculture等杂志发表SCI论文20余篇,参编研究生《水产动物免疫学》教材一部。
研究方向和内容
研究方向为水产动物免疫与病害学,主要研究内容包括:(1)利用免疫学与分子生物学尤其是前沿组学的理论与技术,研究鱼类粘膜免疫系统的细胞分型、机体与病原相互作用的分子机制;(2)水产鱼类关键疾病(例如罗非鱼柱形病、石斑鱼肠孢子虫病等)的快速准确检测技术和高效防控策略的开发与应用;(3)水产鱼类关键疾病的抗病基因和分子标记的筛选,以及抗病育种研究。相关研究丰富了水产动物免疫学的研究内容,推进了水产鱼类健康养殖与安全有效疾病防控策略的开发。
主持科研项目
国家自然科学基金青年项目,罗非鱼鼠李糖凝集素(OnRBL)介导柱状黄杆菌粘附侵染的分子机制,2024-01至2026-12,主持。
罗非鱼重要细菌性病原人工感染模型的建立及抗病品系选育项目,横向课题,2023-05至2025-05,主持。
海南省自然科学基金项目, 罗非鱼鳃粘膜组织细胞分型, 2020-12 至 2023-12,主持。
海南省重大科技计划项目-子课题 高体鰤人工繁育与安全生产关键技术研究与应用示范-疾病防控任务,2021-12 至 2024-12,主持。
广东省水产经济动物病原生物学及流行病学重点实验室开放课题,罗非鱼柱状黄杆菌病原侵染机制研究,2021-09 至 2023-09, 主持。
永利集团高层次人才校级科研启动项目,海南重要养殖鱼类分子免疫机制研究,2020-01到2024-12,主持。
代表论文
Dongdong Zhang, Gengfu Zhou, Wilawan Thongda, Chao Li, Zhi Ye, Honggang Zhao, Benjamin H. Beck, Haitham Mohammed, Eric Peatman. Early divergent responses to virulent and attenuated vaccine isolates of Flavobacterium columnare in channel catfish, Ictalurus punctatus. 2024, 144: 109248.
Peibo Wang#1, Yongcan Zhou#1, Bei Wang, Ahmed Elaswad, Shifeng Wang, Weiliang Guo, Dongdong Zhang*. Single-cell suspension preparation from Nile tilapia intestine for single-cell sequencing, Journal of Visualized Experiments, 2023, (192): 1-12
Dongdong Zhang, Haitham Mohammed, Zhi Ye, Melanie A. Rhodes, Wilawan Thongda, Honggang Zhao, Lauren N Jescovitch, S Adam Fuller, D Allen Davis, Eric Peatman. Transcriptomic profiles of Florida pompano (Trachinotus carolinus) gill following infection by the ectoparasite Amyloodinium ocellatum. Fish and Shellfish Immunology, 2022,125:171-179.
Dongdong Zhang, Wilawan Thongda, Chao Li, Honggang Zhao, Benjamin H. Beck, Haitham Mohammed, Covadonga R. Arias, Eric Peatman*. More than just antibodies: Protective mechanisms of a mucosal vaccine against fish pathogen Flavobacterium columnare. Fish and Shellfish Immunology, 2017, 71: 160-170.
Dongdong Zhang, Benjamin H. Beck, Honggang Zhao, Wilawan Thongda, Zhi Ye, Qifan Zeng, Craig A. Shoemaker, S. Adam Fuller, Eric Peatman. L-Rhamnose-binding lectins (RBLs) in Nile tilapia, Oreochromis niloticus: Characterization and expression profiling in mucosal tissues. Fish and Shellfish Immunology, 2018, 72: 426-435.
Dongdong Zhang, Benjamin H. Beck, Miles Lange, Honggang Zhao, Wilawan Thongda, Zhi Ye, Chao Li, Eric Peatman*. Impact of oral and waterborne administration of rhamnolipids on the susceptibility of channel catfish (Ictalurus punctatus) to Flavobacterium columnare infection, Fish and Shellfish Immunology, 2017, 60: 44-49.
Yangen Zhou#1, Dongdong Zhang#1, Eric Peatman, Melanie A. Rhodes, Jun Liu, D. Allen Davis*, Effects of various levelsof dietary copper supplementation with copper sulfate and copper hydroxychloride on Pacific white shrimp Litopenaeus vannamei performance and microbial communities. Aquaculture, 2017, 476: 94-105.
Chengbin Gao#1, Baofeng Su#1, Dongdong Zhang#1, Ning Yang, Lin Song, Qiang Fu, SHUN- Zhou, Fenghau Tan, Chao Li. L-rhamnose-binding lectins (RBLs) in turbot (Scophthalmus maximus L.): Characterization and expression profiling in mucosal tissues. Fish and Shellfish Immunology, 2018, 80: 264-273.
Yun Sun#1, Dongdong Zhang#1, Jianzhi Shi#1, Guisen Chen, Ying Wu, Yang Shen, Zhenjie Cao, Linlin Zhang*, Yongcan Zhou*, A chromosome-level genome assembly and annotation of the humpback grouper Cromileptes altivelas. bioRxiv 2020.06.22.164277; doi: https://doi.org/10.1101/2020.06.22.164277.
Zhengqiang Chen, Dongdong Zhang, Jing Xing*, Wenbin Zhan, Effects of temperature on haemocyte and granulocyte counts and expressions of immunity-related genes in haemocytes of scallop Chlamys farreri after Vibrio anguillarum Infection. J. Ocean Univ. China. (Oceanic and Coastal Sea Rese). 2019, 5: 1-11.
招生专业
水生生物学博士、水产养殖学术硕士、渔业发展专业硕士
联系方式
电子邮箱:zdd88312@hainanu.edu.cn
办公室:南海海洋资源利用国家重点实验室 517